I'm nearing the end of a prototyping/proof of concept phase for a side project I'm working on, and trying to decide on some larger scale application design decisions. The app is a project management system tailored more towards the agile development process. One of the decisions I need to make is whether or not to go with a traditional multi-page application or a single page application.
All data has to be available via some sort of API - this is a big advantage for my use case as I want to have an API to my application anyway. Right now about 60-70% of my calls to get/update data are done through a REST API. Doing a single page application will allow me to better test my REST API since the application itself will use it. It also means that as the application grows, the API itself will grow since that is what the application uses; no need to maintain the API as an add-on to the application.
More responsive application - since all data loaded after the initial page is kept to a minimum and transmitted in a compact format (like JSON), data requests should generally be faster, and the server will do slightly less processing.
There are also other things that are kind of double edged swords. For example, with single page applications, the data processed for each request can be a lot less since the application will be asking for the minimum data it needs for the particular request, however it also means that there could be a lot more small request to the server. I'm not sure if that is a good or bad thing.
What are some of the advantages and disadvantages of single page web applications that I should keep in mind when deciding which way I should go for my project?